| 摘要 |
<p>Alkinols and alkine-diols are prepared by reacting a solution of acetylene or an acetylene hydrocarbon with a solution of an aldehyde or ketone in the presence of copper acetylide or other ethinylation catalyst while maintaining the pressure in excess of 250 lbs. per square inch. Suitable solvents for the acetylene or acetylene hydrocarbon are acetone, propargyl alcohol, tetrahydrofuran and dioxan, and suitable aldehydes and ketones are formaldehyde, acetaldehyde, benzaldehyde, acetone, methylethyl ketone and acetophenone. Temperatures up to 200 DEG C. may be employed when using small catalyst particles in the so-called fluidized catalyst technique. In an example, a solution of acetylene in acetone and a solution of formaldehyde in water are introduced by means of a proportioning pump into a tubular reaction column packed with copper acetylide catalyst deposited on silica gel, the pressure being maintained at 1,000 lbs. per square inch. A table is given showing the amounts of propargyl alcohol and butine-diol produced at temperatures of 95 DEG and 125 DEG C. and with mol. ratios of formaldehyde to acetylene of 1.67 and 0.8.</p> |
