| 发明名称 |
ACCELERATION OF WOUND HEALING BY A TISSUE INHIBITOR OF METALLOPROTEINASES (TIMP) LINKED TO GLYCOSYLPHOSPHATIDYLINOSITOL (GPI)-ANCHORS |
| 摘要 |
<p>The present invention relates to fusion constructs of glycosylphosphatidylinositol (GPI)-anchored tissue inhibitors of metalloproteinases (TIMPs) and their use for the treatment of cancer and in regenerative medicine. By this approach, the GPI-anchored TIMP proteins are incorporated into the surface membrane of cells. The fusion constructs of the present invention are effective agents in accelarating wound healing.</p> |
| 申请公布号 |
EP2504027(A1) |
申请公布日期 |
2012.10.03 |
| 申请号 |
EP20100784451 |
申请日期 |
2010.11.22 |
| 申请人 |
GMG BERATUNGS- UND BETEILIGUNGS VERWALTUNGS GMBH;NELSON, PETER JON |
发明人 |
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| 分类号 |
A61K38/57;A61K38/00;A61K47/48;A61P17/02;C07K14/81;C07K19/00;C12N15/62 |
主分类号 |
A61K38/57 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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