发明名称 Compound having affinity for amyloid
摘要 A compound that has affinity with amyloid, exhibits sufficiently rapid clearance from normal tissues, and is suppressed in toxicity such as mutagenicity is provided, which is represented by the following formula (1): or a salt thereof, wherein R1 is a group selected from hydrogen, hydroxyl group, carboxyl group, sulfate group, amino group, nitro group, cyano group, an alkyl substituent with one to 4 carbon atoms or an alkoxy substituent with one to 4 carbon atoms; R2 is a radioactive halogen substituent; and m is an integer of 0 to 2, and a low-toxic diagnostic agent for Alzheimer's disease comprising a compound represented by the above formula or a salt thereof is also provided.
申请公布号 US8277777(B2) 申请公布日期 2012.10.02
申请号 US20070308715 申请日期 2007.06.21
申请人 TANIFUJI SHIGEYUKI;HAYASHI AKIO;NAKAMURA DAISAKU;TAKASAKI SHINYA;STOREY ANTHONY EAMON;BOUVET DENIS RAYMOND CHRISTOPHE;NIHON MEDI-PHYSICS CO., LTD.;GE HEALTHCARE LIMITED 发明人 TANIFUJI SHIGEYUKI;HAYASHI AKIO;NAKAMURA DAISAKU;TAKASAKI SHINYA;STOREY ANTHONY EAMON;BOUVET DENIS RAYMOND CHRISTOPHE
分类号 A61K51/00;A61M36/14;C07D491/02 主分类号 A61K51/00
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