| 发明名称 |
HEPATOCYTE GROWTH FACTOR RECEPTOR ANTAGONISTS AND USES THEREOF |
| 摘要 |
Hepatocyte growth factor (HGF) receptor antagonists are provided. The HGF receptor antagonists include HGF receptor antibodies and fragments thereof. The HGF receptor antagonists can be employed to block binding of HGF to HGF receptors or substantially inhibit HGF receptor activation. The HGF receptor antagonists may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treating cancer using the HGF receptor antagonists are also provided. |
| 申请公布号 |
CA2223269(C) |
申请公布日期 |
2012.10.02 |
| 申请号 |
CA19962223269 |
申请日期 |
1996.05.31 |
| 申请人 |
GENENTECH, INC. |
发明人 |
SCHWALL, RALPH H.;TABOR, KELLY HELEN |
| 分类号 |
C12N15/13;G01N33/566;A61K38/00;A61K39/395;A61K45/00;A61P35/00;C07K1/22;C07K14/71;C07K14/76;C07K16/28;C07K16/46;C07K19/00;C10G65/02;C10G65/04;C10G65/08;C12N5/10;C12N5/18;C12N15/02;C12N15/09;C12N15/12;C12P21/08;C12R1/91;G01N33/574;G01N33/577 |
主分类号 |
C12N15/13 |
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