| 发明名称 |
Substituted isoquinoline and isoquinolinone derivatives as inhibitors of Rho-kinase |
| 摘要 |
The invention relates to 6-substituted isoquinoline and isochinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds. |
| 申请公布号 |
US8278294(B2) |
申请公布日期 |
2012.10.02 |
| 申请号 |
US20090487403 |
申请日期 |
2009.06.18 |
| 申请人 |
PLETTENBURG OLIVER;HOFMEISTER ARMIN;BRENDEL JOACHIM;LOHN MATTHIAS;SANOFI |
发明人 |
PLETTENBURG OLIVER;HOFMEISTER ARMIN;BRENDEL JOACHIM;LOHN MATTHIAS |
| 分类号 |
A61K31/397 |
主分类号 |
A61K31/397 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
