URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C

摘要

URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C AbstractPresent application relates to the compounds of formula I useful to treat hepatitis C (HCV) infections. In the structure of the disclosed compounds is the uracil or thymine derivative linked via a phenylene into either fused 2-ring cyclic system (R6) or alternatively via additional two-atom linker (L) to a 5-6 membered monocycle (R6). Application further discloses polymorphs and pseudopolymorphs of two specific compounds: N-(6(3-t-buty1-5- (2,4dioxo3,4dihydropyrimidin1(2H)y1)(2methoxyphenyl)naphthalen2yemethanesulfonamide &(E)-N-(4(3-t-buty1-5-(2,4-dioxo-3)4-dihydropyrimidin-1(2H)-3,02-methoxy-styryl phenyOmethanesulfonamide.No Suitable figure