| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a positive allosteric modulator subtype 5 ([mGluR5]) of a new metabotropic receptor. <P>SOLUTION: The invention relates to new compounds of formula (I) wherein W is a (C<SB POS="POST">4</SB>-C<SB POS="POST">7</SB>) cycloalkyl, or the like, P is a (C<SB POS="POST">5</SB>-C<SB POS="POST">7</SB>) heterocycloalkyl, or the like, Q is a cycloalkyl, aryl, or the like, A is azo -N=N-, ethyl, ethenyl, ethynyl, -NR<SB POS="POST">8</SB>C(=O)-, -NR<SB POS="POST">8</SB>C(=O)-O-, -NR<SB POS="POST">8</SB>C(=O)-NR<SB POS="POST">9</SB>, NR<SB POS="POST">8</SB>S(=O)<SB POS="POST">2</SB>-, -C(=O)NR8-, -O-C(=O)NR<SB POS="POST">8</SB>-, -S-, -S(=O)-, -SO(=O)<SB POS="POST">2</SB>-, -S(=O)<SB POS="POST">2</SB>NR<SB POS="POST">8</SB>, or the like. <P>COPYRIGHT: (C)2012,JPO&INPIT |
