发明名称 PYRAZOLONE COMPOUNDS USEFUL FOR TREATMENT OF CEREBROVASCULAR DISORDER ASSOCIATED WITH ISCHEMIC STROKE
摘要 <P>PROBLEM TO BE SOLVED: To provide a compound as an effective ingredient, that is a pyrazolone compound, as an improved effective ingredient that responds to demands in pharmaceutical markets and that is effective for the treatment of diseases relating to ischemic stroke. <P>SOLUTION: A drug for the treatment of cerebrovascular disorders associated with insufficient cerebral circulation such as ischemic stroke is provided, wherein the drug comprises a pharmaceutically effective amount of a pyrazolone compound expressed by structural formula (I) or a pharmaceutically acceptable salt thereof, or a pseudo-polymorphic form thereof, and wherein the drug is administered at a controlled dose in such a manner that the plasma concentration of unchanged form is kept constant for a predetermined period of time and that the compound exhibits a higher effect. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012184263(A) 申请公布日期 2012.09.27
申请号 JP20120148294 申请日期 2012.07.02
申请人 MITSUBISHI TANABE PHARMA CORP 发明人 SACHI TOSHI;NAKANO TAKUMA;SUZUKI HIROKO
分类号 A61K31/4152;A61P9/10;A61P25/14;A61P25/28;C07D231/22 主分类号 A61K31/4152
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