发明名称 |
ANTAGONIST ANTI-IL-7 RECEPTOR ANTIBODIES AND METHODS |
摘要 |
The present invention provides antagonizing antibodies that bind to interleukin-7 receptor (IL-7R). The invention further provides a method of obtaining such antibodies and antibody-encoding nucleic acids. The invention further relates to therapeutic methods for use of these antibodies and antigen-binding portions thereof for the treatment and/or prevention of type 2 diabetes and immunological disorders, including type 1 diabetes, multiple sclerosis, rheumatoid arthritis, graft-versus-host disease, and lupus. |
申请公布号 |
SG182811(A1) |
申请公布日期 |
2012.09.27 |
申请号 |
SG20120056610 |
申请日期 |
2011.02.24 |
申请人 |
RINAT NEUROSCIENCE CORPORATION |
发明人 |
LIN, CHIA-YANG;LEE, LI-FEN;ZHAI, WENWU |
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