发明名称 |
DISPLAY OF DISULFIDE LINKED DIMERIC PROTEINS ON FILAMENTOUS PHAGE |
摘要 |
<p>Methods are provided for the display of a complex homodimer protein on the surface of a bacteriophage particle and combinatorial synthetic libraries of such proteins displayed as a fusion polypeptide with filamentous phage pIX coat protein. Heterodimeric or more complex interchain bonded structure, such as disulfide-linked, multimeric proteins, may be displayed using the method of the invention.</p> |
申请公布号 |
EP2501808(A1) |
申请公布日期 |
2012.09.26 |
申请号 |
EP20100832033 |
申请日期 |
2010.11.15 |
申请人 |
JANSSEN BIOTECH, INC. |
发明人 |
HUANG, CHICHI;SPINKA-DOMS, TRACY;FRANSSON, JOHAN |
分类号 |
C12N15/00 |
主分类号 |
C12N15/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|