发明名称 OPTICAL TRANSILLUMINATION AND REFLECTANCE SPECTROSCOPY TO QUANTIFY DISEASE RISK
摘要 The present invention uses spectroscopic tissue volume measurements using non-ionizing radiation to detect pre-disease transformations in the tissue, which increase the risk for this disease in mammals. The method illuminating a volume of selected tissue of a mammal with light having wavelengths covering a pre-selected spectral range, detecting light transmitted through, or reflected from, volume of selected tissue, and obtaining a spectrum of the detected light. The spectrum of detected light is then represented by one or more basis spectral components, an error term, and an associated scalar coefficient for each of the basis spectral components. The associated scalar coefficient is calculated by minimizing the error term. The associated scalar coefficient of the each of the basis spectral components is correlated with a pre-selected property of the selected tissue known to be indicative of susceptibility of the tissue for the pre-selected disease to obtain the susceptibility for the mammal to developing the pre-selected disease.
申请公布号 CA2467407(C) 申请公布日期 2012.09.25
申请号 CA20022467407 申请日期 2002.11.20
申请人 UNIVERSITY HEALTH NETWORK 发明人 WILSON, BRIAN C.;NIELSEN, MICHELLE K.;LILGE, LOTHAR
分类号 A61B5/00 主分类号 A61B5/00
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