发明名称 |
Implantable Devices and Methods for Treatment of Pain by Delivery of Fentanyl and Fentanyl Congeners |
摘要 |
The invention features devices and methods for treatment of pain. The drug delivery device is a drug delivery system adapted for whole implantation in a subject and to provide pain relief by delivery of fentanyl or a fentanyl congener (e.g., sufentanil) over a protracted period of time (e.g., at least 3 days or more than 3 days). The device comprises a housing defining a reservoir that contains a drug formulation, a pump operatively connected to the housing so as to facilitate movement of drug out of the reservoir and out of the device, and a thermal expansion element which defines a flow pathway comprising a thermal expansion channel to accommodate thermal expansion of formulation in the reservoir. The device can further comprise a valve positioned within the flow pathway so as to prevent movement of drug out of the reservoir prior to use. |
申请公布号 |
US2012239007(A1) |
申请公布日期 |
2012.09.20 |
申请号 |
US201213355217 |
申请日期 |
2012.01.20 |
申请人 |
GILLIS EDWARD M.;LAIDLAW BARBARA J. F.;CULWELL JOHN;FILICE JAMES A.;WICKMAN PETER;POUTIATINE ANDREW J.;DINKA JOHN S.;JOHNSON RANDOLPH M.;THEEUWES FELIX |
发明人 |
GILLIS EDWARD M.;LAIDLAW BARBARA J. F.;CULWELL JOHN;FILICE JAMES A.;WICKMAN PETER;POUTIATINE ANDREW J.;DINKA JOHN S.;JOHNSON RANDOLPH M.;THEEUWES FELIX |
分类号 |
A61J1/10;A61M5/168;A61F2/00;A61F2/02;A61K9/00;A61K9/22;A61K31/4468;A61K31/4535;A61K47/10;A61K47/14;A61K47/26;A61M5/14;A61M5/142;A61M5/145;A61M5/148;A61M31/00;A61P25/04 |
主分类号 |
A61J1/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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