SURFACE COATING FOR BIOMOLECULE IMMOBILISATION AND MINIMISATION OF NON-SPECIFIC BINDING ON SURFACES FOR BIOMEDICAL DIAGNOSTICS

摘要

A solid substrate coating capable of swelling by a factor of at least 2 on contact with an aqueous solution. The solid substrate coating may be prepared by activating the surface of a solid substrate by treatment with a plasma, depositing a first layer of siloxane onto the surface of the solid substrate using plasma, and depositing a second layer of at least on chemical functionality on top of the first layer using plasma.