发明名称 |
METHOD OF TREATING MALIGNANCIES IN MAMMALS |
摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention refers to biotechnology, more specifically to using recombinant proteins for treating mammals suffering malignancies. A method of treating involves the injections of an antitumour agent of a protein factor specific to malignant cells. The antitumour agent is presented by a recombinant peptide of molecular weight approximately 16 kDa containing methionine residue, a fragment of human kappa casein of 24 to 134 amino acid residue and C-terminal histidine tract. The agent is introduced intravenously daily in dose 8-100 mg/kg of body weight; the therapeutic course is 2-6 days. ^ EFFECT: invention allows higher effectiveness of antitumour therapy. ^ 5 dwg, 4 ex |
申请公布号 |
RU2461566(C1) |
申请公布日期 |
2012.09.20 |
申请号 |
RU20110116027 |
申请日期 |
2011.04.22 |
申请人 |
UCHREZHDENIE ROSSIJSKOJ AKADEMII NAUK INSTITUT KHIMICHESKOJ BIOLOGII I FUNDAMENTAL'NOJ MEDITSINY SIBIRSKOGO OTDELENIJA RAN (IKHSFM SO RAN);ZAKRYTOE AKTSIONERNOE OBSHCHESTVO "BIOSAN R" (ZAO"BIOSAN R") |
发明人 |
KOVAL' OL'GA ALEKSANDROVNA;KALEDIN VASILIJ IVANOVICH;KULIGINA ELENA VLADIMIROVNA;SEMENOV DMITRIJ VLADIMIROVICH;FOMIN ALEKSANDR SERGEEVICH;POTAPENKO MIRASLAVA OLEGOVNA;RIKHTER VLADIMIR ALEKSANDROVICH |
分类号 |
A61K38/17;A61P35/00;C07K14/47 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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