发明名称 |
METHODS AND MATERIALS FOR PROLONGING USEFUL STORAGE OF RED BLOOD CELL PREPARATIONS AND PLATELET PREPARATIONS |
摘要 |
This document provides methods and materials for enhancing the storage capabilities of red blood cell preparations. For example, methods and materials for using CO2 to store red blood cells in a manner that (a) reduces the level of glucose or 2,3-DPG consumption of or reduces the level of 2,3-DPG production by a red blood cell preparation, (b) reduces the level of lactate formation by a red blood cell preparation, and/or (c) reduces the pH level of a red blood cell preparation are provided. Such methods and materials can result in prolonging the useful lifespan of the red blood cells of the red blood cell preparation. This document also provides methods and materials involved in prolonging useful storage of platelet preparations. For example, methods and materials for storing platelets in a manner that reduces platelet metabolism, that preserves platelet function, and/or that reduces the risk of bacterial contamination are provided. |
申请公布号 |
WO2012125955(A2) |
申请公布日期 |
2012.09.20 |
申请号 |
WO2012US29510 |
申请日期 |
2012.03.16 |
申请人 |
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH;DYNASIL BIOMEDICAL CORPORATION;JOYNER, MICHAEL J.;ERICSON, DANIEL GRANT |
发明人 |
JOYNER, MICHAEL J.;ERICSON, DANIEL GRANT |
分类号 |
A01N1/02;A61J1/05;C12N5/02 |
主分类号 |
A01N1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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