发明名称 |
SOLID FORMS OF N-(4-(7-AZABICYCLO[2.2.1]HEPTAN-7-YL)-2-(TRIFLUOROMETHYL)PHENYL)-4-OXO-5-(TRIFLUOROMETHYL)-1,4-DIHYDROQUINOLINE-3-CARBOXAMIDE |
摘要 |
The present invention relates to substantially crystalline and solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide (Form A-HCl, Form B, Form B-HCl, or any combination of these forms), pharmaceutical compositions thereof, and methods of treatment therewith. |
申请公布号 |
KR20120102645(A) |
申请公布日期 |
2012.09.18 |
申请号 |
KR20127013139 |
申请日期 |
2010.10.21 |
申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
ZHANG BEILI;KRAWIEC MARIUSZ;LUISI BRIAN;MEDEK ALES |
分类号 |
C07D487/08;A61K31/407;A61P11/00;A61P29/00 |
主分类号 |
C07D487/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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