| 发明名称 |
1,4 THIAZEPINES/SULFONES AS BACE1 AND/OR BACE2 INHIBITORS |
| 摘要 |
<p>The present invention relates to 1,4 Thiazepines/Sulfones of formula (I) having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.</p> |
| 申请公布号 |
CA2825077(A1) |
申请公布日期 |
2012.09.13 |
| 申请号 |
CA20122825077 |
申请日期 |
2012.02.28 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
HILPERT, HANS;ROGERS-EVANS, MARK;ROMBACH, DIDIER |
| 分类号 |
C07D417/12;A61K31/554;A61P3/10;A61P25/16;C07D513/04 |
主分类号 |
C07D417/12 |
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