发明名称 Non-natural sphingolipid analogs and uses thereof
摘要 This disclosure provides a composition useful for inhibiting caveolar endocytosis, plasma membrane microdomain formation, virus binding and infection, transmembrane signaling, and integrin function in cells. The composition is composed of non-natural analogs of sphingolipids, and may have applications in the treatment or amelioration of diseases associated with caveolar endocytosis, plasma membrane microdomain formation, transmembrane signaling, and integrin function. Methods for making and using the described composition are also provided.
申请公布号 US8263576(B2) 申请公布日期 2012.09.11
申请号 US20070839024 申请日期 2007.08.15
申请人 PAGANO RICHARD E.;BITTMAN ROBERT;MARKS DAVID L.;KITA HIROHITO;TAKHTER RAMANDEEP S.;MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 发明人 PAGANO RICHARD E.;BITTMAN ROBERT;MARKS DAVID L.;KITA HIROHITO;TAKHTER RAMANDEEP S.
分类号 A61K31/715 主分类号 A61K31/715
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