发明名称 STABILIZED COMPOSITION OF CANDESARTAN CILEXETIL AND METHOD FOR PRODUCING THE SAME
摘要 <P>PROBLEM TO BE SOLVED: To provide a stabilized composition of candesartan cilexetil having excellent environmental stability by improving all of temperature stability, humidity stability and photostability of candesartan cilexetil and a method for producing the same. <P>SOLUTION: The composition comprises candesartan cilexetil and at least any sugar of mannitol and lactose and is obtained by kneading a mixture of the candesartan cilexetil and the sugar with water or a water-containing organic solvent to give wet powder and compression molding the powder. A preferable embodiment is that the composition further contains a binder. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012171954(A) 申请公布日期 2012.09.10
申请号 JP20110038682 申请日期 2011.02.24
申请人 ELMED EISAI KK 发明人
分类号 A61K31/4188;A61K9/20;A61K47/10;A61K47/26;A61K47/32;A61K47/36;A61K47/38;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P13/12;A61P43/00;C07D403/10 主分类号 A61K31/4188
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