发明名称 |
MEDICINAL FORMS OF PHOSPHOLIPID PREPARATIONS AND METHODS FOR THEIR PREPARATION |
摘要 |
A method for producing a pharmaceutical composition comprising a combination of phospholipid and glycyrrhizic acid or a pharmaceutically acceptable salt thereof, which composition is hydratable to produce an injectable medicinal form, said method comprising subjecting a mixture of phospholipid and an aqueous solution of glycyrrhizic acid or a pharmaceutically acceptable salt thereof and a carbohydrate to homogenization, for example at 800-1200 bar pressure at a temperature of less than 90° C., and subjecting the product of the homogenization to a sublimation drying step to produce said composition. Compositions obtainable using this method, and hydrated forms of these ready for administration by injection form further aspects of the invention.
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申请公布号 |
US2010179100(A1) |
申请公布日期 |
2010.07.15 |
申请号 |
US20060063581 |
申请日期 |
2006.08.11 |
申请人 |
GUSEVA MARIYA KIRILLOVNA;UCHAIKIN VASILIY FEDOROVICH;TIKHONOVA ELENA GEORGIEVNA;IPATOVA OLGA MIKHAILOVNA |
发明人 |
GUSEVA MARIYA KIRILLOVNA;UCHAIKIN VASILIY FEDOROVICH;TIKHONOVA ELENA GEORGIEVNA;IPATOVA OLGA MIKHAILOVNA |
分类号 |
A61K31/704;A61P1/16;A61P29/00;A61P31/12;A61P37/08 |
主分类号 |
A61K31/704 |
代理机构 |
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地址 |
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