| 摘要 |
<p>Compositions and methods for delivering, in an oral environment, chlorhexidine in combination with beneficial ions selected from calcium, phosphate, fluoride, silver, and carbonate ions are described. These compositions and methods may involve the formation of chlorhexidine compounds either prior to use or in situ. Representative compounds include chlorhexidine fluoride (ChxF), chlorhexidine phosphate (ChxP), chlorhexidine calcium fluoride (ChxCF), chlorhexidine phosphate fluoride (ChxPF), chlorhexidine calcium phosphate (ChxCP), chlorhexidine calcium phosphate fluoride (ChxCPF), chlorhexidine silver calcium phosphate fluoride (ChxACPF) or the compositions or methods which will form these noble chlorhexidine compounds when applied to the tooth. Two or more of these chlorhexidine compounds may be formed as an aggregate, or one or more of these chlorhexidine compounds may be formed as an aggregate with calcium fluoride (CaF2).</p> |
