发明名称 |
USING GAME THEORY IN IDENTIFYING COMPOUNDS THAT BIND TO TARGETS |
摘要 |
A method performed by one or more processing devices includes retrieving information indicative of compounds and mutations of a target; generating one or more predictions of binding affinities of the compounds to the mutations; generating a simulation for introducing at least one of the compounds in response to at least one of the mutations; identifying, based on an application of a game theory algorithm to the simulation and to the one or more predictions, an equilibrium of the simulation; and identifying, from the equilibrium, a subset of the compounds with an increased binding affinity to the mutations relative to other binding affinities of other of the compounds. |
申请公布号 |
WO2012118825(A2) |
申请公布日期 |
2012.09.07 |
申请号 |
WO2012US26966 |
申请日期 |
2012.02.28 |
申请人 |
CARNEGIE MELLON UNIVERSITY;LANGMEAD, CHRISTOPHER, J.;KAMISETTY, HETUNANDAN |
发明人 |
LANGMEAD, CHRISTOPHER, J.;KAMISETTY, HETUNANDAN |
分类号 |
G06F19/00 |
主分类号 |
G06F19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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