发明名称 |
BAALC EXPRESSION AS A DIAGNOSTIC MARKER FOR ACUTE LEUKEMIA |
摘要 |
Overexpression of the gene, BAALC, in biological samples from a patient is prognostic for tumor aggressiveness and unfavorable patient outcome. The present invention provides polynucleotide primers and probes for assaying for overexpression of BAALC transcripts. Kits containing the primers and probes are also provided. Also provided are antibodies for assaying for overexpression of BAALC proteins as well as peptide immunogens for producing the anti-BAALC antibodies. The present invention also provides methods for characterizing acute myelogenous leukemia, chronic myelogenous leukemia and prostate cancer in a patient, base on detection of BAALC overexpression. |
申请公布号 |
US2012225426(A1) |
申请公布日期 |
2012.09.06 |
申请号 |
US201213370760 |
申请日期 |
2012.05.04 |
申请人 |
TANNER STEPHAN M.;DE LA CHAPELLE ALBERT |
发明人 |
TANNER STEPHAN M.;DE LA CHAPELLE ALBERT |
分类号 |
C12Q1/68;C07H21/00;C07H21/04;C07K16/18;G01N33/574 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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