<p>The invention provides small molecule mimics of the Smac peptide that are dimers or dimer-like compounds having two binding domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.</p>
申请公布号
EP2493879(A2)
申请公布日期
2012.09.05
申请号
EP20100830467
申请日期
2010.10.28
申请人
JOYANT PHARMACEUTICALS, INC.
发明人
SUN, HAIZHOU;XU, XIAOMING;ZHOU, MING;HARRAN, SUSAN;HANSON, GUNNAR, JAMES