发明名称 |
METHODS FOR EXPANSION AND ANALYSIS OF CULTURED HEMATOPOIETIC STEM CELLS |
摘要 |
<p>Methods and kits for propagating hematopoietic stem cells are provided. The methods comprise culturing cells in medium comprising one or more angiopoietin-like proteins, under conditions sufficient for expansion of HSCs. Angiopoietin-like proteins include angiopoietin-like protein 2, angiopoietin-like protein 3, angiopoietin-like protein 4, angiopoietin-like protein 5, angiopoietin-like protein 7, and microfibrillar-associated glycoprotein (Mfap4). Methods for identifying hematopoietic stem cells are provided and isolated hematopoietic stem cells are also provided.</p> |
申请公布号 |
EP1899457(B1) |
申请公布日期 |
2012.09.05 |
申请号 |
EP20060771063 |
申请日期 |
2006.05.23 |
申请人 |
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH |
发明人 |
ZHANG, CHENGCHENG;LODISH, HARVEY |
分类号 |
C12N5/077;C12N5/078;C12N5/0789 |
主分类号 |
C12N5/077 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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