发明名称 |
(PYRIDIN-4-YL)BENZYLAMIDES AS ALLOSTERIC MODULATORS OF ALPHA 7 NACHR |
摘要 |
The present invention relates to (pyridin-4-yl)benzylamides derivatives and pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy. The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulators having the capability to increase the efficacy of nicotinic receptor agonists.
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申请公布号 |
CA2824350(A1) |
申请公布日期 |
2012.08.30 |
申请号 |
CA20122824350 |
申请日期 |
2012.02.23 |
申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
DE BOECK, BENOIT CHRISTIAN ALBERT GHISLAIN;ROMBOUTS, GEERT;LEENAERTS, JOSEPH ELISABETH;MACDONALD, GREGOR JAMES |
分类号 |
C07D213/38;A61K31/44;A61P1/00;A61P17/06;A61P25/14;A61P25/16;A61P25/18;A61P25/28;A61P25/34;A61P31/00;C07D213/82;C07D401/12;C07D405/12;C07D413/10;C07D413/12;C07D413/14 |
主分类号 |
C07D213/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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