发明名称 |
Polyanionic multivalent macromolecules for intracellular targeting of proliferation and protein synthesis |
摘要 |
The present invention relates generally to methods and compositions for targeting of intracellular molecules involved in proliferation and protein synthesis of activated cells using polyanionic multivalent macromolecules. In particular aspect, multiple sulfate groups linked to polyol are specifically targeted to the cytoplasm and nucleus of proliferating and activated cells. The invention further comprises novel polyanionic macromolecular compounds and formulations. |
申请公布号 |
AU2011212742(A1) |
申请公布日期 |
2012.08.30 |
申请号 |
AU20110212742 |
申请日期 |
2011.01.31 |
申请人 |
MIVENION GMBH |
发明人 |
LICHA, KAI;SCHIRNER, MICHAEL;WELKER, PIA;HAAG, RAINER;WEINHART, MARIE;PAULUS, FLORIAN |
分类号 |
A61K47/48;A61K49/00;A61K49/12;C08G83/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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