Dermal micro organs, methods and apparatuses for producing and using the same

摘要

Embodiments of the present invention provide Dermal Micro Organs (DMOs), methods and apparatuses for producing the 5 same. Some embodiments of the invention provide a DMO including a plurality of dermal components, which substantially retain the micro-architecture and three dimensional structure of the dermal tissue from which they are derived, having dimensions selected so as to allow 10 passive diffusion of adequate nutrients and gases to cells of the DMO and diffusion of cellular waste out of the cells so as to minimize cellular toxicity and concomitant death due to insufficient nutrition and accumulation of waste in the DMO. Some embodiments of the invention is provide methods and apparatuses for harvesting the DMO. An apparatus for harvesting the DMO may include, according to some exemplary embodiments, a support configuration to support a skin-related tissue structure from which the DMO is to be harvested, and a cutting tool able to separate 20 the DMO from the skin-related tissue structure. Other embodiments are described and claimed. 2379595_1 (GHMatters) 18/08110