发明名称 USE OF AN ADRENAL HORMONE-MODIFYING AGENT
摘要 The present invention relates to a method of treating a disease or disorder characterised by increased stress hormone levels and/or decreased androgen hormone levels in a subject, comprising administering to the subject a therapeutically effective amount of a compound represented by formula (I): wherein n is 1 or 3; R is hydrogen or --C(O)N(Ra)(Rb) wherein Ra and Rb are independently --(C1-C4) alkyl, or --(C1-C4) alkyl-(C5-C7) aryl, wherein each of Ra and Rb is optionally substituted by --(C1-C4) alkoxy; R1, R2, and R3, are independently hydrogen, halogen, cyano or --(C6-C10) aryl, wherein said --(C6-C10) aryl is optionally substituted by halogen, with the proviso that no more than one of R1, R2, and R3 is hydrogen; and R4 and R5 are hydrogen; or a pharmaceutically acceptable salt thereof.
申请公布号 SG182393(A1) 申请公布日期 2012.08.30
申请号 SG20120049995 申请日期 2011.01.13
申请人 NOVARTIS AG 发明人 HU, QI-YING;KSANDER, GARY;MEREDITH, ERIK;MONOVICH, LAUREN G.;PAPILLON, JULIEN;SCHUMACHER, CHRISTOPH
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