发明名称 |
IMIDAZO[1,2-b]PYRIDAZINE DERIVATIVES AND THEIR USE AS PDE10 INHIBITORS |
摘要 |
The present invention relates to novel imidazo[1,2-b]pyridazine derivatives which are inhibitors of the phosphodiesterase 10 enzyme (PDE10) and which are useful for the treatment or prevention of neurological, psychiatric and metabolic disorders in which the PDE10 enzyme is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, to the use of such compounds or pharmaceutical compositions for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases. |
申请公布号 |
US2012220581(A1) |
申请公布日期 |
2012.08.30 |
申请号 |
US201013505187 |
申请日期 |
2010.10.27 |
申请人 |
PASTOR-FERNANDEZ JOAQUIN;BARTOLOME-NEBREDA JOSE MANUEL;MACDONALD GREGOR JAMES;CONDE-CEIDE SUSANA;DELGADO-GONZALEZ OSCAR;VANHOOF GRETA CONSTANTIA PETER;VAN GOOL MICHIEL LUC MARIA;MARTIN-MARTIN MARIA LUZ;ALONSO-DE DIEGO SERGIO-ALVAR;JANSSEN-CILAG, S.A. |
发明人 |
PASTOR-FERNANDEZ JOAQUIN;BARTOLOME-NEBREDA JOSE MANUEL;MACDONALD GREGOR JAMES;CONDE-CEIDE SUSANA;DELGADO-GONZALEZ OSCAR;VANHOOF GRETA CONSTANTIA PETER;VAN GOOL MICHIEL LUC MARIA;MARTIN-MARTIN MARIA LUZ;ALONSO-DE DIEGO SERGIO-ALVAR |
分类号 |
A61K31/5377;A61K31/5025;A61P3/00;A61P25/00;A61P25/04;A61P25/14;A61P25/18;A61P25/22;A61P25/28;A61P25/30;C07D487/04 |
主分类号 |
A61K31/5377 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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