发明名称 |
ANTAGONISTS OF PCSK9 |
摘要 |
Antagonists of human proprotein convertase subtilisin-kexin type 9 (PCSK9) are disclosed. Said antagonists are effective in the inhibition of PCSK9 function and thereby provide compositions of matter useful for the treatment of conditions associated with PCSK9 activity. The present invention further discloses nucleic acids encoding PCSK9 antagonists as well as methods of making and using PCSK9 antagonists. |
申请公布号 |
US2012219558(A1) |
申请公布日期 |
2012.08.30 |
申请号 |
US201013497663 |
申请日期 |
2010.09.15 |
申请人 |
NI YAN;SITLANI AYESHA;PANDIT SHILPA;LEWIS DALE;SHEN XUN;LOBO SHARON;MCCABE TIMOTHY;CONDRA JON;CUBBON ROSE;WANG FUBAO |
发明人 |
NI YAN;SITLANI AYESHA;PANDIT SHILPA;LEWIS DALE;SHEN XUN;LOBO SHARON;MCCABE TIMOTHY;CONDRA JON;CUBBON ROSE;WANG FUBAO |
分类号 |
A61K39/395;A61P7/00;C07K16/40;C12N1/21;C12N15/13;C12N15/63;C12P21/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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