摘要 |
<p>A series of imidazo[1,2-α]pyrazine derivatives, being potent modulators of human TNFαactivity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorder; and oncological disorders.</p> |