发明名称 |
METHODS OF USING ANTI-CD3 ANTIBODIES TO PREVENT WEIGHT GAIN |
摘要 |
<p>Provided herein are methods of administering anti-CD3 antibodies or antigen binding fragments to a human for decreasing weight gain or increasing weight loss. In certain embodiments, the human exhibits a body mass index (BMI) or greater than or equal to about 27. In certain embodiments, the anti-CD3 antibody or antigen binding fragment does not bind or has reduced binding to at least one class of Fc (gamma) receptor.</p> |
申请公布号 |
EP2490719(A2) |
申请公布日期 |
2012.08.29 |
申请号 |
EP20100825627 |
申请日期 |
2010.10.20 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
BRENNAN, AOIFE;MCKEE, CHARLOTTE;RINGLER, DOUGLAS;VAICKUS, LOU |
分类号 |
A61K39/395;A61P3/04;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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