USE OF CHIMERIC ANTIGEN RECEPTOR-MODIFIED T CELLS TO TREAT CANCER
摘要
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain.
申请公布号
WO2012079000(A4)
申请公布日期
2012.08.23
申请号
WO2011US64191
申请日期
2011.12.09
申请人
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;JUNE, CARL, H.;LEVINE, BRUCE, L.;PORTER, DAVID, L.;KALOS, MICHAEL, D.
发明人
JUNE, CARL, H.;LEVINE, BRUCE, L.;PORTER, DAVID, L.;KALOS, MICHAEL, D.
