| 发明名称 |
Compositions and methods for diagnosing and treating cancer |
| 摘要 |
An isolated antibody that specifically binds to an extracellular domain of human DLL4 and affects growth of a tumor comprising cancer stem cells is described. Also described is a method of treating cancer comprising administering a therapeutically effective amount of an anti-DLL4 antibody. |
| 申请公布号 |
AU2007305443(B2) |
申请公布日期 |
2012.08.23 |
| 申请号 |
AU20070305443 |
申请日期 |
2007.09.28 |
| 申请人 |
ONCOMED PHARMACEUTICALS, INC. |
发明人 |
AXELROD, FUMIKO;HOEY, TIMOTHY;GURNEY, AUSTIN;SATYAL, SANJEEV |
| 分类号 |
C07K16/00;A61K39/00;C07H21/04;C12N15/00;C12P21/08 |
主分类号 |
C07K16/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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