<p>The present invention relates to the Pharmaceutical capsule comprising the tablet, pellets or granules comprising (i) a core ii) the first drug layer comprising 30-90% of Dexlansoprazole of the total weight of the Dexlansoprazole filled into the capsules iii) a first sub coating layer iv) an extended release layer comprising the pH dependently soluble polymer or the combinations thereof, said polymeric substance is soluble in the pH range of 6.0 to 7.5. v) a second sub coating on the extended release layer vi) the second drug layer comprising 10-70% of the Dexlansoprazole of the total weight of the Dexlansoprazole filled into the capsules vii) a third sub coating layer on the second drug layerviii) an enteric coating layer comprising the enteric coating polymer such that the 10-70% of the active ingredient is released in the pH range of no less than 5.0 to no more than 6.0.</p>