| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a human heavy chain variable part antibody which binds with neurotrophin receptor p75, a method of measurement using the antibody, and a pharmaceutical composition or a reagent containing the antibody. <P>SOLUTION: The human heavy chain variable part antibody which is active to bind with neurotrophin receptor p75 is successfully obtained by repeating a step of selecting a phage for expressing the human heavy chain variable part antibody a plurality of times which binds with neurotrophin receptor p75-expressing human cultured cell. Thus provided are the human heavy chain variable part antibody which binds with neurotrophin receptor p75 in human cell or human tissue, a composition for detecting neurotrophin receptor p75 using the antibody, and a neurotrophin receptor p75-binding pharmaceutical composition. <P>COPYRIGHT: (C)2012,JPO&INPIT |
