Trypsin-like serine protease inhibitors, and their preparation and use
摘要
The invention provides compounds that are effective as inhibitors of human plasmin and plasma kallikrein, and that are useful for the prevention of blood loss and as components of fibrin adhesives. The invention further provides methods of making and using the compounds.
申请公布号
AU2011210802(A1)
申请公布日期
2012.08.23
申请号
AU20110210802
申请日期
2011.01.28
申请人
THE MEDICINES COMPANY (LEIPZIG) GMBH
发明人
HEROLD, PETER;DAGHISH, MOHAMMED;JELAKOVIC, STJEPAN;LUDWIG, FRIEDRICH-ALEXANDER;REICHELT, CLAUDIA;SCHULZE, ALEXANDER;SCHWEINITZ, ANDREA