发明名称 OXYGEN-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS.
摘要 <p>The present invention relates to compounds of the formula I, wherein A, D, E, G, R10, R30, R40, R50 and R60 have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. They are inhibitors of the protease cathepsin A, and are useful for the treatment of diseases such as atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases, for example. The invention furthermore relates to processes for the preparation of the compounds of the formula I, their use and pharmaceutical compositions comprising them.</p>
申请公布号 MX2012008635(A) 申请公布日期 2012.08.23
申请号 MX20120008635 申请日期 2011.01.26
申请人 SANOFI.* 发明人 KLAUS WIRTH;JOSEF PERNERSTORFER;SVEN RUF;CHRISTIAN BUNING;HERMAN SCHREUDER;BODO SCHEIPER;THOMAS OLPP;THORSTEN SADOWSKI;GEORG HORSTICK
分类号 C07D231/20;A61K31/415;A61P9/00;A61P11/00;A61P13/12;A61P25/28;A61P29/00;A61P37/00;C07D231/22;C07D401/04;C07D401/12;C07D403/12;C07D405/12;C07D413/12;C07D417/12 主分类号 C07D231/20
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