| 发明名称 |
PROCESS FOR THE PREPARATION OF (R,S)-NICOTINE |
| 摘要 |
A process for (R,S)-nicotine is described. Condensation of 1-(but-1-enyl)pyrrolidin-2-one with nicotinic acid ester gave 1-(but-1-enyl)-3-nicotinoylpyrrolidin-2-one which on treatment with an acid and a base gave myosmine. Myosmine was converted to (R,S)-nicotine by reduction followed by N-methylation. |
| 申请公布号 |
US2012209006(A1) |
申请公布日期 |
2012.08.16 |
| 申请号 |
US201113080995 |
申请日期 |
2011.04.06 |
| 申请人 |
DIVI MURALI KRISHNA PRASAD;PADAKANDLA GUNDU RAO;RAO MYSORE ASWATHA NARAYANA;KATTA HARI BABU;DIVI'S LABORATORIES LIMITED |
发明人 |
DIVI MURALI KRISHNA PRASAD;PADAKANDLA GUNDU RAO;RAO MYSORE ASWATHA NARAYANA;KATTA HARI BABU |
| 分类号 |
C07D401/04;C07D401/06 |
主分类号 |
C07D401/04 |
| 代理机构 |
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代理人 |
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