发明名称 |
NEW USE OF PERIOSTIN |
摘要 |
<p>PURPOSE: Periostin for inducing movement of nerve stem cells is provided to prevent and treat brain diseases and nervous diseases. CONSTITUTION: A kit for treating cancer contains periostin, cells which secrete periostin, and nerve cells which express suicide gene or anti-oncogene. The kit further contains an anticancer precursor which is converted to anticancer materials by the suicide gene. Periostin has an amino acid sequence of sequence number 1-4. The suicide gene is HSV-TK(herpes simplex virus-thymidine kinase) or cytosine deaminase. The anti-oncogene is PEX, Trail, or IFN-beta. A composition for preventing and treating neural disease or brain diseases contains periostin or the cells or neural stem cells secreting periostin.</p> |
申请公布号 |
KR20120089996(A) |
申请公布日期 |
2012.08.16 |
申请号 |
KR20110137189 |
申请日期 |
2011.12.19 |
申请人 |
AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION |
发明人 |
LEE, MYUNG AE;JEON, JEONG YONG |
分类号 |
A61K35/30;A61K35/12;C07K14/47;C12N5/0797 |
主分类号 |
A61K35/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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