发明名称 |
FOLATE RECEPTOR ALPHA AS A DIAGNOSTIC AND PROGNOSTIC MARKER FOR FOLATE RECEPTOR ALPHA-EXPRESSING CANCERS |
摘要 |
The present invention provides methods and kits for assessing whether a subject is afflicted with an FRα-expressing cancer, methods and kits for predicting the progression of ovarian cancer in a subject afflicted with an FRα-expressing cancer, methods and kits for assessing the level of risk that a subject will develop an FRα-expressing cancer, and methods of stratifying a subject with an FRα-expressing cancer into cancer therapy groups. The methods involve determining the level of folate receptor alpha (FRα) which is not bound to a cell in a sample derived from the subject and comparing this level with the level of FRαin a control sample.
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申请公布号 |
US2012207771(A1) |
申请公布日期 |
2012.08.16 |
申请号 |
US201113289892 |
申请日期 |
2011.11.04 |
申请人 |
O'SHANNESSY DANIEL J.;GRASSO LUIGI;WAN SHANHONG;CHAO QIMIN;SOMERS ELIZABETH BROOKE;MORPHOTEK INC. |
发明人 |
O'SHANNESSY DANIEL J.;GRASSO LUIGI;WAN SHANHONG;CHAO QIMIN;SOMERS ELIZABETH BROOKE |
分类号 |
A61K39/395;A61P35/00;G01N21/64;G01N33/574 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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