发明名称 |
NOVEL METHOD FOR QUANTIFYING PROTEINS BY MASS SPECTROMETRY |
摘要 |
The present invention relates to a method for the quantitative detection of a target protein in a sample, in which the second-generation fragment ions are detected for providing a series of quantitative measurements, at least one of which is correlated to the amount of proteotypic peptide generated and to the amount of target protein in the sample, characterized in that the selected first-generation fragment ion having a mass (m/z)2 is a doubly-charged peptide having a proline and/or a histidine in position 1. |
申请公布号 |
US2012208224(A1) |
申请公布日期 |
2012.08.16 |
申请号 |
US201013322173 |
申请日期 |
2010.05.21 |
申请人 |
LEMOINE JEROME;SALVADOR ARNAUD;CHARRIER JEAN-PHILIPPE;FORTIN TANGUY;BIOMERIEUX;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;UNIVERSITE CLAUDE BERNARD LYON I |
发明人 |
LEMOINE JEROME;SALVADOR ARNAUD;CHARRIER JEAN-PHILIPPE;FORTIN TANGUY |
分类号 |
G01N27/62 |
主分类号 |
G01N27/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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