发明名称 ANTI-ALPHA-V INTEGRIN ANTIBODY FOR THE TREATMENT OF PROSTATE CANCER
摘要 The invention is directed to the treatment of prostate cancer by means of antibodies. Above all, the invention relates to the administration of an anti-alpha-v integrin (receptor) antibody to patients suffering from prostate cancer, especially castration- resistant prostate cancer (CRPC), optionally accompanied by lymph node and bone tissue metastases (mCRPC). In particular, the invention relates to the therapy of said patients by means of the anti-angiogenic antibody DI17E6 and structural mutants thereof.
申请公布号 WO2012107211(A1) 申请公布日期 2012.08.16
申请号 WO2012EP00548 申请日期 2012.02.07
申请人 MERCK PATENT GMBH;HOFFMANN, AXEL;LANNERT, HEINRICH;BRISCHWEIN, KLAUS;PIPP, FREDERIC CHRISTIAN;REINDL, JUERGEN;GROLL, KARIN;ZUEHLSDORF, MICHAEL;PFAFF, OTMAR;RAAB, SABINE;DAU, ULRIKE;DESTENAVES, BENOIT 发明人 HOFFMANN, AXEL;LANNERT, HEINRICH;BRISCHWEIN, KLAUS;PIPP, FREDERIC CHRISTIAN;REINDL, JUERGEN;GROLL, KARIN;ZUEHLSDORF, MICHAEL;PFAFF, OTMAR;RAAB, SABINE;DAU, ULRIKE;DESTENAVES, BENOIT
分类号 A61K39/395;A61P39/00;C07K16/28;C07K16/30 主分类号 A61K39/395
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