LECTIN PRESENTING CELL, LECTIN LIBRARY, AND SCREENING METHOD FOR LECTIN

摘要

The present invention addresses the problem of providing: a modified lectin library which is useful for finding a lectin that is capable of binding to a specific sugar chain; modified lectins which constitute the modified lectin library; and a method for generating a modified lectin library. The present invention provides a lectin presenting cell which comprises: an expression vector that comprises a nucleic acid encoding a fusion protein that comprises a lectin, a transmembrane domain and an anchor domain comprising a signaling motif that transmits a signal into the cell when the lectin is bound to a sugar chain; and a reporter gene which is expressed when a signal is transmitted into the cell via the signaling motif. The present invention also provides a library which comprises the lectin presenting cell, and the like.