发明名称 |
RECOMBINANT ANTIBODIES AGAINST H1N1 INFLUENZA |
摘要 |
Antibodies that bind with high affinity to swine H1N1 virus are described. In vivo experiments showed that one such antibody is able to fully protect mice challenged with a lethal dose of swine H1N1 virus. The antibody is also able to cure mice in a therapeutic setting when treated as late as up to 60 hours (2.5 days) after infection with swine H1N1 virus. Also described are recombinant forms of this antibody. |
申请公布号 |
EP2486054(A2) |
申请公布日期 |
2012.08.15 |
申请号 |
EP20100822829 |
申请日期 |
2010.10.12 |
申请人 |
EMORY UNIVERSITY;THE UNIVERSITY OF CHICAGO |
发明人 |
WRAMMERT, JENS;AHMED, RAFI;WILSON, PATRICK |
分类号 |
C07K16/10;A61K39/42;A61P31/16;C12N15/13 |
主分类号 |
C07K16/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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