| 发明名称 |
Materials and methods to potentiate cancer treatment |
| 摘要 |
Compounds that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods to inhibit the DNA-PK biological activity, methods to sensitize cells the agents that cause DNA lesions, and methods to potentiate cancer treatment are disclosed. |
| 申请公布号 |
US8242115(B2) |
申请公布日期 |
2012.08.14 |
| 申请号 |
US20070708163 |
申请日期 |
2007.02.16 |
| 申请人 |
HALBROOK JAMES;KESICKI EDWARD A.;BURGESS LAURENCE E.;SCHLACHTER STEPHEN T.;EARY CHARLES T.;SCHIRO JUSTIN G.;HUANG HONGMEI;EVANS MICHAEL;HAN YONGXIN;LUITPOLD PHARMACEUTICALS, INC. |
发明人 |
HALBROOK JAMES;KESICKI EDWARD A.;BURGESS LAURENCE E.;SCHLACHTER STEPHEN T.;EARY CHARLES T.;SCHIRO JUSTIN G.;HUANG HONGMEI;EVANS MICHAEL;HAN YONGXIN |
| 分类号 |
C07D311/86;A61K31/35;A61K45/06;A61P35/00;C07C309/66;C07D209/36;C07D211/42;C07D211/46;C07D213/40;C07D213/50;C07D213/74;C07D213/75;C07D219/06;C07D219/16;C07D233/54;C07D235/26;C07D239/48;C07D277/24;C07D277/42;C07D277/46;C07D277/54;C07D279/12;C07D295/096;C07D295/112;C07D295/13;C07D295/135;C07D295/155;C07D295/185;C07D295/215;C07D295/30;C07D307/83;C07D309/10;C07D311/30;C07D333/22;C07D401/06;C07D405/04;C07D405/12;C07D417/12;C07D471/04;C07D521/00;C07F9/6533;C07F9/6578 |
主分类号 |
C07D311/86 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
