发明名称 |
In vivo and ex vivo gene transfer into renal tissue using gutless adenovirus vectors |
摘要 |
A method for treating a renal disease in a subject is disclosed. The method includes administering into a kidney of the subject with an effective amount of a gutless adenoviral vector containing a polynucleotide encoding a therapeutic agent. The gutless adenoviral vector contains the nucleotide sequence of SEQ ID NO:13 or SEQ ID NO:15 and expresses the therapeutic agent in a kidney tissue of the subject.
|
申请公布号 |
US8242095(B2) |
申请公布日期 |
2012.08.14 |
申请号 |
US20100778340 |
申请日期 |
2010.05.12 |
申请人 |
SEHGAL LAKSHMAN R.;WONG JONATHAN;BIOVEC, LLC |
发明人 |
SEHGAL LAKSHMAN R.;WONG JONATHAN |
分类号 |
A61K48/00;C07H21/04 |
主分类号 |
A61K48/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|