发明名称 |
Anti-CD16 binding molecules |
摘要 |
<p>The present invention relates to binding molecules that specifically bind to the human Fc gamma receptor expressed on the surface of natural killer (NK) cells and macrophages (i.e. FcγRIIIA), and in particular binding molecules that specifically bind the A form FcγRIII but do not bind to the B form of FcγRIII, as well as to the use of such binding molecules in the diagnosis and treatment of disease. The invention further extends to polynucleotides encoding such binding molecules, host cells comprising such polynucleotides and methods of producing binding molecules of the invention using such host cells.</p> |
申请公布号 |
AU2006251283(B2) |
申请公布日期 |
2012.08.02 |
申请号 |
AU20060251283 |
申请日期 |
2006.05.26 |
申请人 |
AFFIMED THERAPEUTICS AG |
发明人 |
KNACKMUSS, STEFAN HANS JOACHIM;KIPRIJANOV, SERGEJ;LITTLE, MELVYN;REUSCH, UWE;LE GALL, FABRICE;HOFFMANN, KARIN |
分类号 |
C07K16/28;A61K39/395;A61K47/48 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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