发明名称 |
PYRAZOLE COMPOUNDS AS CRTH2 ANTAGONISTS |
摘要 |
The present invention relates to pyrazole compounds of formula (1a) or (1b) and pharmaceutically acceptable salts thereof, wherein Ra, Rb, Rc, Rd, Y1, y2, y3, y4, y5, Z, R1, R2, n and R3 have one of the meanings as indicated in the specification and claims, to their use as medicaments, to pharmaceutical formulation containing said compounds and to pharmaceutical formulations said compounds in combination with one or more active substances. The compounds have CRTH2 antagonistic activity. |
申请公布号 |
WO2012101043(A1) |
申请公布日期 |
2012.08.02 |
申请号 |
WO2012EP50830 |
申请日期 |
2012.01.20 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;ANDERSKEWITZ, RALF;MARTYRES, DOMNIC;OOST, THORSTEN;RIST, WOLFGANG;SEITHER, PETER |
发明人 |
ANDERSKEWITZ, RALF;MARTYRES, DOMNIC;OOST, THORSTEN;RIST, WOLFGANG;SEITHER, PETER |
分类号 |
C07D403/12;A61K31/4155;A61P29/00;C07D407/12;C07D409/12 |
主分类号 |
C07D403/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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